File Name: oxygen saturation targets and outcomes in extremely preterm infants .zip
Metrics details. FiO 2 -C is provided by commercially available and CE-marked ventilators with an FiO 2 -C algorithm intended for use in newborn infants. This will ensure an appropriate assessment of safety and efficacy before FiO 2 -C may be implemented as standard therapy. The study is registered at www.
Oxygen is essential for life. Yet, the too-liberal use of oxygen is toxic. Impressively, all 3 trial groups embarked on rigorously designed trials that would facilitate an eventual meta-analysis. Synnes A, Miller SP. JAMA Pediatr.
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Jump to navigation. Review question : Is it better to target a lower or higher level of oxygen for babies born very early? Background : Giving additional 'supplemental' oxygen to babies born very early 'extremely preterm infants' who have breathing difficulties has been common practice since the s. Despite this, there is little agreement as to what levels of oxygen will maximise short- or long-term survival and development. Technology 'pulse oximetry' that can easily measure the level of oxygen in a baby's blood oxygen saturation has been in widespread use since the s. Despite this, until recently there were no randomised trials that had tested whether it is better to target lower or higher oxygen saturation levels in extremely preterm infants, from birth or soon thereafter.
In phase 3, oxygen saturation histograms constructed from pulse-oximeter data were used as daily feedback to nurses and compliance with oxygen-targeting was measured again. The mean SD percent time spent within target SpO 2 range increased from Effective implementation of oxygen targeting policy and feedback using oxygen saturation histograms may improve compliance with oxygen targeting. This is a preview of subscription content, access via your institution.
The Spanish Association of Pediatrics has as one of its main objectives the dissemination of rigorous and updated scientific information on the different areas of pediatrics. Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. CiteScore measures average citations received per document published. Read more.
SUPPORT investigators and publishing editors, heads of government study funding agencies, and many ethicists have argued that informed consent was adequate because the two oxygen saturation target ranges studied fell within a range commonly recommended in guidelines. Data were extracted on intended and achieved oxygen saturation levels as determined by pulse oximetry. Blinded targeting of a low narrow range resulted in significantly lower achieved oxygen saturations and a doubling of time spent below the lower limit of the intended range compared to usual care practices. Descriptions of major differences between the interventions studied and commonly practiced usual care, as well as potential risks associated with these differences, are essential elements of adequate informed consent. This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
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Празднично одетые испанцы выходили из дверей и ворот на улицу, оживленно разговаривая и смеясь. Халохот, спустившись вниз по улочке, смачно выругался. Сначала от Беккера его отделяла лишь одна супружеская пара, и он надеялся, что они куда-нибудь свернут.
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