File Name: breast cancer etiology and pathophysiology .zip
Studies have shown that your risk for breast cancer is due to a combination of factors.
Breast cancer is the most common invasive cancer in women and the second leading cause of cancer death in women after lung cancer. Advances in screening and treatment for breast cancer have improved survival rates dramatically since The chance of any woman dying from breast cancer is around 1 in 38 2. The ACS estimate that , women will receive a diagnosis of invasive breast cancer, and 62, people will receive a diagnosis of noninvasive cancer in In the same year, the ACS report that 41, women will die as a result of breast cancer.
Studies have shown that your risk for breast cancer is due to a combination of factors. The main factors that influence your risk include being a woman and getting older. Most breast cancers are found in women who are 50 years old or older. Some women will get breast cancer even without any other risk factors that they know of.
Having a risk factor does not mean you will get the disease, and not all risk factors have the same effect. Most women have some risk factors, but most women do not get breast cancer.
If you have breast cancer risk factors, talk with your doctor about ways you can lower your risk and about screening for breast cancer. Research suggests that other factors such as smoking, being exposed to chemicals that can cause cancer, and changes in other hormones due to night shift working also may increase breast cancer risk. If you have a strong family history of breast cancer or inherited changes in your BRCA1 and BRCA2 genes, you may have a high risk of getting breast cancer.
You may also have a high risk for ovarian cancer. Talk to your doctor about ways to reduce your risk, such as medicines that block or decrease estrogen in your body, or surgery. Skip directly to site content Skip directly to page options Skip directly to A-Z link. Breast Cancer. Section Navigation. Facebook Twitter LinkedIn Syndicate. Minus Related Pages.
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Crit Rev Oncol Hematol. Aging: Risk increases with advancing age. Risk at age 40 is and risk at age 80 is Height : Taller women, both pre- and postmenopausal, have a slightly increased risk; likely correlated with hormonal stimulation. Arch Intern Med. Weight : High body-mass index BMI is a risk factor for post menopausal women, likely due to adipose tissue production of estrogen via aromatase.
Breast cancer most often involves glandular breast cells in the ducts or lobules. Most patients present with an asymptomatic mass discovered during examination or screening mammography. Diagnosis is confirmed by biopsy. Treatment usually includes surgical excision, often with radiation therapy, with or without adjuvant chemotherapy, hormone therapy, or both. About , new cases of invasive breast cancer and about 42, deaths from it are expected in In addition, about 48, new cases of in situ breast cancer are expected in 2.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, limiting alcohol intake, eating plenty of vegetables , fruits , and whole grains , vaccination against certain infectious diseases, limiting consumption of processed meat and red meat , and limiting exposure to direct sunlight. In , about Greek physicians Hippocrates and Galen, among others, noted similarity of crabs to some tumors with swollen veins. The word was introduced in English in the modern medical sense around Cancers comprise a large family of diseases that involve abnormal cell growth with the potential to invade or spread to other parts of the body. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often form a mass or lump, but may be distributed diffusely.
Breast cancer, the most frequently occurring cancer in women, is a major public health problem, with 1,, estimated new cases worldwide with nearly , related deaths. Breast cancer is highly heterogeneous in its pathological characteristics, some cases showing slow growth with excellent prognosis, while others being aggressive tumors. Current predictions and statistics suggest that both worldwide incidence of breast cancer and related mortality are on the rise. According to American Cancer Society, one in eight women in the United States will develop breast cancer in her lifetime. It has been predicted that the worldwide incidence of female breast cancer will reach approximately 3. These numbers reflect the magnitude of breast cancer incidence, its effect on society worldwide and the need for urgency for preventive and treatment measures.
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